About Us
Based at the Children’s Hospital of Philadelphia and The University of Pennsylvania’s Perelman School of Medicine, our lab seeks to reconstitute the complex interface between mechanical and chemical signaling in the context of cell migration in complex microenvironments and tissue crowding. We combine several fluorescent microscopy approaches with microfluidics, microfabrication techniques and organ-on-a chip devices to apply controlled and precise confinement to cultured cells and impose different degrees of mechanical stress to their nuclei.
Diversity statement: I believe that scientific communication is key, and collaborations among people and institutions is essential to science progress. I will be mindful about having a supportive learning environment as I promote the ideals for a diverse workplace where people from different backgrounds work in harmony to pursue their professional goals, without discrimination. I am fully committed to creating a welcoming lab that promotes the goals of diversity, equity and inclusion in educating the next generation of academic scientists.
Our connections
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Pennsylvania Muscle Institute (PMI)
The PMI is an interdisciplinary group of research investigators. Our goal is to discover the mechanisms of muscle function, muscle disease and motile biological systems through innovative and cross-disciplinary research, and to apply these discoveries to new therapies.
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Cell and Molecular Biology Graduate Group (CAMB)
CAMB is an interdisciplinary graduate program, providing rigorous training in modern cell and molecular biology. Within this integrated program are six discipline areas: Cancer Biology; Cell Biology, Physiology, and Metabolism; Developmental, Stem Cell, and Regenerative Biology; Genetics and Epigenetics; Gene Therapy and Vaccines and Microbiology, Virology, and Parasitology.
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Pharmacology Graduate Group (PGG)
Our training program is designed to provide students with knowledge in basic biomedical science as well as both depth and breadth of training in pharmacology. More recently, with the growing number of faculty involved in pharmacogenomics, proteomics, and metabolomics, the ability to analyze and understand large data sets has become a necessity, and training is offered in bioinformatics and genome science.
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Penn Center for Engineering Mechanobiology (CEMB)
The Center for Engineering MechanoBiology (CEMB) is a multi-institution Science and Technology Center funded by the National Science Foundation (NSF) to advance the study of mechanical forces in molecules, cells, and tissues in plants and animals. Committed to inclusion, CEMB recruits, educates, and mentors individuals from all cultural, scientific, and socio-economic backgrounds.
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Bioengineering Graduate Group (BGG)